Results 181 to 190 of about 409,192 (258)

Self‐Discontinuity as a Barrier to Identity and Behaviour Change: Evidence From Smoking Cessation

open access: yesEuropean Journal of Social Psychology, EarlyView.
ABSTRACT Extensive research has shown that resistance to behaviour change is often driven by the management of self‐related threats, traditionally conceptualized as threats to self‐esteem. The present research offers a novel perspective by examining behaviour change as a threat to self‐continuity (i.e., the perceived stability of one's self‐image over ...
Jérôme Blondé   +1 more
wiley   +1 more source

Prospective evaluation of a seizure detection wearable device for timely interventions in an epilepsy monitoring unit

open access: yesEpilepsia, EarlyView.
Abstract Objective This study aimed to evaluate the real‐world performance of a wrist‐worn seizure detection device for timely clinical interventions within an epilepsy monitoring unit (EMU). Methods We conducted a prospective observational study involving patients admitted to the EMU at a tertiary care center.
Amirhossein Jahani   +9 more
wiley   +1 more source

Memantine treatment in individuals with GRIN gain‐of‐function variants is associated with improvements in behavior, development, and seizure frequency

open access: yesEpilepsia, EarlyView.
Abstract Objective GRIN‐related disorders due to pathogenic variants in GRIN1, GRIN2A, GRIN2B, or GRIN2D genes are associated with altered N‐methyl‐D‐aspartate receptor (NMDAR) function. Functional changes include gain (GoF) and loss of receptor function (LoF). Clinical reports describing the use of the NMDAR blocker memantine in GRIN‐related disorders
Maike Karnstedt   +17 more
wiley   +1 more source

Development and validation of a deep survival model to predict time to seizure from routine electroencephalography

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate a deep survival model (EEGSurvNet) that analyzes routine electroencephalography (EEG) to predict individual seizure risk over time, comparing its performance to traditional clinical predictors such as interictal epileptiform discharges (IEDs).
Émile Lemoine   +5 more
wiley   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

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