Results 201 to 210 of about 409,192 (258)

Isolated absence epilepsy associated with a de novo FBXW7 missense variant in the F‐box domain

open access: yesEpilepsia Open, EarlyView.
Abstract The FBXW7 gene encodes a substrate‐recognition component of the Skp1‐Cul1‐F‐box (SCF) E3 ubiquitin ligase complex, which targets key regulatory proteins for proteasomal degradation. Recently, loss‐of‐function FBXW7 variants have been associated with a novel neurodevelopmental disorder characterized by heterogeneous clinical features.
Anees Muhammad   +10 more
wiley   +1 more source

Implementing pragmatic case finding to address alcohol use in general practice: a mixed methods feasibility study. [PDF]

open access: yesScand J Prim Health Care
Potthoff S   +7 more
europepmc   +1 more source

Scalp fast oscillations detected by high‐density EEG as a noninvasive predictor of surgical outcome in temporal lobe epilepsy with hippocampal sclerosis

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate whether scalp oscillatory patterns—particularly scalp fast oscillations (SFOs) (>30 Hz) detected using 256‐channel high‐density EEG (HD‐EEG)—are associated with and can predict surgical outcomes in patients with drug‐resistant temporal lobe epilepsy with hippocampal sclerosis (TLE‐HS) undergoing anterior temporal ...
Pongsakorn Kongsakorn   +4 more
wiley   +1 more source

Loss of cyclin‐dependent kinase‐like 5 results in susceptibility to audiogenic seizures in mice

open access: yesEpilepsia Open, EarlyView.
Abstract CDKL5 deficiency disorder (CDD) is a severe neurodevelopmental encephalopathy characterized by early‐onset, treatment‐resistant epilepsy. Mice lacking CDKL5 display several clinically relevant phenotypes, but spontaneous seizures are not consistently reported, and it is unknown if CDD model mice are susceptible to sensory stimulus‐triggered ...
Jordan Higgins   +4 more
wiley   +1 more source

Tracking Glucose Trends, Unveiling Clinical Patterns: Insights From Continuous Glucose Monitoring in Patients at the Extreme of BMI and Eating Disorders Psychopathology

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Disturbances of glucose homoeostasis are claimed to act as both a consequence and maintaining factor in eating disorders (EDs). This study explored glucose trends and their association with real‐time food intake and self‐report eating psychopathology in a sample of patients with anorexia nervosa (AN) and binge‐eating disorder (BED ...
Marianna Rania   +8 more
wiley   +1 more source

Eating Attitudes and Anthropometric Indices of Adult Women in Performance Dance: A Case‐Control Study in Greece

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Dancers are at an increased risk of developing eating disorders and health issues. The aim of this case‐control study was to compare dietary intake, anthropometric indices and eating attitudes of adult professional dancers to their age‐ and sex‐matched non‐dancer females.
Alexandra Foscolou   +9 more
wiley   +1 more source

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