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Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
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Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Gene-environment interplay in reading performance
Amaia Carrión-Castillo +2 more
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Visual Symptoms and Reading Performance
Optometry and Vision Science, 1993Clinical observation indicates that visual asthenopic symptoms are frequently associated with reading for long periods of time. We investigated the relation between visual symptoms and standard measures of reading performance in 78 university students.
J D, Grisham, M M, Sheppard, W U, Tran
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Reading Performance in Infantile Nystagmus
Ophthalmology, 2013To characterize reading deficits in infantile nystagmus (IN), to determine optimal font sizes for reading in IN, and to investigate whether visual acuity (VA) and severity of nystagmus are good indicators of reading performance in IN.Prospective cross-sectional study.Seventy-one participants with IN (37 idiopathic, 34 with albinism) and 20 age-matched ...
Niraj, Barot +3 more
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Beginning readers' reading performance and reading habits
Journal of Research in Reading, 2005This study investigated the prospective relationships between reading performance and reading habits among Finnish children during the first and second grades of primary school. One hundred and ninety‐five children were examined twice during their first primary school year and once during the spring term of Grade 2.
Ulla Leppänen +2 more
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High-performance reading machines
Proceedings of the IEEE, 1991The architecture of a reading machine designed to achieve a high rate of correct interpretation of text as well as high speed in performing the interpretation is described. The refinement of the architecture for a specialized reading machine, to find and interpret addresses on a stream of postal letters, is also described.
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Greece and Rome, 1987
Simon Goldhill's Reading Greek Tragedy is a welcome publication – not for its originality but because it makes available an important and eclectic body of critical approaches to Greek texts. Goldhill gives no quarter to the idea that the Greekless reader cannot deal with complex theoretical arguments.
openaire +1 more source
Simon Goldhill's Reading Greek Tragedy is a welcome publication – not for its originality but because it makes available an important and eclectic body of critical approaches to Greek texts. Goldhill gives no quarter to the idea that the Greekless reader cannot deal with complex theoretical arguments.
openaire +1 more source

