Results 291 to 300 of about 2,355,686 (332)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Gene-environment interplay in reading performance

open access: gold
Amaia Carrión-Castillo   +2 more
openalex   +2 more sources

Visual Symptoms and Reading Performance

Optometry and Vision Science, 1993
Clinical observation indicates that visual asthenopic symptoms are frequently associated with reading for long periods of time. We investigated the relation between visual symptoms and standard measures of reading performance in 78 university students.
J D, Grisham, M M, Sheppard, W U, Tran
openaire   +2 more sources

Reading Performance in Infantile Nystagmus

Ophthalmology, 2013
To characterize reading deficits in infantile nystagmus (IN), to determine optimal font sizes for reading in IN, and to investigate whether visual acuity (VA) and severity of nystagmus are good indicators of reading performance in IN.Prospective cross-sectional study.Seventy-one participants with IN (37 idiopathic, 34 with albinism) and 20 age-matched ...
Niraj, Barot   +3 more
openaire   +2 more sources

Beginning readers' reading performance and reading habits

Journal of Research in Reading, 2005
This study investigated the prospective relationships between reading performance and reading habits among Finnish children during the first and second grades of primary school. One hundred and ninety‐five children were examined twice during their first primary school year and once during the spring term of Grade 2.
Ulla Leppänen   +2 more
openaire   +1 more source

High-performance reading machines

Proceedings of the IEEE, 1991
The architecture of a reading machine designed to achieve a high rate of correct interpretation of text as well as high speed in performing the interpretation is described. The refinement of the architecture for a specialized reading machine, to find and interpret addresses on a stream of postal letters, is also described.
openaire   +1 more source

Reading Greek Performance

Greece and Rome, 1987
Simon Goldhill's Reading Greek Tragedy is a welcome publication – not for its originality but because it makes available an important and eclectic body of critical approaches to Greek texts. Goldhill gives no quarter to the idea that the Greekless reader cannot deal with complex theoretical arguments.
openaire   +1 more source

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