Results 301 to 310 of about 2,791,251 (363)

Evaluating community pharmacists' involvement in patient counselling and health education in Nairobi, Kenya: A cross-sectional study. [PDF]

PLoS One
Manjari SW, Ermias MT.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Differential impacts of digital interactive media and print media on mental health: mediating mechanism of health literacy and group heterogeneity. [PDF]

Front Public Health
Yuan J, Luo L.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Assessing the relationship between sexual health literacy and sexual self-care in women: a cross-sectional study in Iran. [PDF]

Sex Med
Darban F, Heydarikhayat N, Olyaee S, Raeisi N.   +3 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Evaluating the Effectiveness of Generative AI for the Creation of Patient Education Materials on Coronary Heart Disease: A Comparative Study. [PDF]

JMIR Form Res
Jiang X, Liu J, Dai S, Mao X, Cha R, Wu L.   +5 more
europepmc   +1 more source

Exploring digital interaction and positive youth development in a sample of Spanish undergraduates. [PDF]

AIMS Public Health
López-Bermúdez E, Tomé G, Gómez-Baya D.   +2 more
europepmc   +1 more source

Shared book reading to promote mental well-being among young people with and without Down syndrome: a pilot dyadic randomized controlled trial. [PDF]

Front Public Health
Huang X, Long I, Zhang W, Xu J, Smith RD.   +4 more
europepmc   +1 more source