Results 81 to 90 of about 219,284 (275)

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

The performance of haematuria reagent strips for the rapid mapping of urinary schistosomiasis: field experience from Southern Sudan.

open access: yes, 2009
The implementation of programmes to control neglected tropical diseases (NTDs) requires up-to-date information on the prevalence and distribution of each NTD.
Kolaczinski, Jan   +6 more
core   +1 more source

Frequency of blood glucose monitoring in relation to glycaemic control: observational study with diabetes database [PDF]

open access: yes, 1999
Objectives: To investigate patterns of self monitoring of blood glucose concentration in diabetic patients who use insulin and to determine whether frequency of self monitoring is related to glycaemic control.
Evans, Josie   +17 more
core   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Screening with reagent strips. [PDF]

open access: yesBMJ, 1971
M, Briggs   +3 more
openaire   +2 more sources

Sensitivity and specificity of reagent strips in screening of Kenyan children for Schistosoma haematobium infection

open access: yes, 1984
The reliability of using urinalysis reagent strips, which semi-quantitatively measure hematuria and proteinuria, to correctly select urine specimens found by microscopy to have Schistosoma haematobium eggs was studied in 359 previously unscreened Kenyan ...
Oduori, M L   +3 more
core  

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

Screening of Tanzanian women of childbearing age for urinary schistosomiasis: validity of urine reagent strip readings and self-reported symptoms

open access: yesBulletin of the World Health Organization, 2000
The screening of women of childbearing age for haematuria, leukocyturia and proteinuria to detect urinary schistosomiasis can be confounded by several factors such as menstruation, pregnancy and genitourinary infections. We therefore undertook a study in
G. Poggensee   +3 more
doaj  

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

open access: yesAdvanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka   +3 more
wiley   +1 more source

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