Results 91 to 100 of about 79,736 (260)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Starlikeness associated with certain strongly functions

Heliyon
Let κ be an analytic function in the open unit disc U in the complex plane with κ(0)=1. Then κ∈K(λ) if and only if κ(t)≺ϕλ(t), where ≺ is a subordination relation and the function ϕλ(t):=(1+t)λ, for ...
Afis Saliu, Kanwal Jabeen, Jianhua Gong, Sarfraz Nawaz Malik, Hala Alaqad   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Coefficient inequalities for certain analytic functions

International Journal of Mathematics and Mathematical Sciences, 2002
For real α(α>1), we introduce subclasses M(α) and N(α) of analytic functions f(z) with f(0)=0 and f′(0)=1 in U. The object of the present paper is to consider the coefficient inequalities for functions f(z) to be in the classes M(α) and N(α).
Junichi Nishiwaki, Shigeyoshi Owa
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Analyticity of the global attractor for the 3D regularized MHD equations

Electronic Journal of Differential Equations, 2016
We study the three-dimensional (3D) regularized magnetohydrodynamics (MHD) equations. Using the method of splitting of the asymptotic approximate solutions into higher and lower Fourier components, we prove that the global attractor of the 3D ...
Caidi Zhao, Bei Li
doaj  

Chebyshev’s Method for Multiple Zeros of Analytic Functions: Convergence, Dynamics and Real-World Applications

Mathematics
This paper deals with the convergence and dynamics of Chebyshev’s method for simple and multiple zeros of analytic functions. We establish a local convergence theorem that provides error estimates and exact domains of initial approximations to guarantee ...
Stoyanka G. Kostadinova, Stoil I. Ivanov
doaj   +1 more source