Results 21 to 30 of about 8,797 (227)

Political Turmoil in ECOWAS: When Politics Prevails Over Law [PDF]

Ученые записки Института Африки Российской академии наук
Several military regimes have recently come to power within the Economic Community of West African States (ECOWAS). This article on the political crisis in ECOWAS examines the main causes of these developments in the region and the approaches of regional
Adu Yao Nikez, Mezyaev Alexander Borisovich   +1 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Conceptual Space for Illiberal Democracy

Politics and Governance
For over a decade, populists have been experimenting with a new political regime–illiberal democracy. Vocal proponents, such as Hungary’s PM Viktor Orbán, develop “democratic illiberalism” as an ideational model for the illiberal‐democratic regime they ...
Ruzha Smilova
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The ecosystem of coups in West Africa: implications for Democracy and Regional Peace

Journal of Central and Eastern European African Studies
The Sahel region of Africa, characterized by political and security fragility has been the theatre of coups that significantly challenged democracy and peace consolidation. Most of the coups operated in recent years have been led by military juntas, who
Faroukou Mintoiba
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Administrative Procedural Law in Russia: Status, Problems and Prospects

Сибирское юридическое обозрение, 2022
Based on the analysis of legal acts, with the involvement of the works of Russian and foreign scientists, the results of modern research, this article describes the current state of the branch of administrative procedural law in Russia.
V. E. Sevryugin
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Hierarchical Multi-Class Deepfake Detection Using EfficientNetB4 for Source Attribution [PDF]

ITM Web of Conferences
The rising of deepfake media (images, videos and audio etc.) has become a major issue in the digital era. Deepfake generation techniques such as Generative Adversarial Networks and Diffusion Models, shows major challenge to individual’s privacy ...
Kumar Mukesh, Choudhary Raviraj, Meena Gaurav   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source