Results 141 to 150 of about 21,871,407 (373)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Functional Situational Awareness for Reliable and Efficient Operation of Hybrid Electric Vehicle Power Systems

open access: yesIEEE Access
Hybrid electric vehicle power systems (VPSs) comprise of limited energy resources and variable load requirements. The functional status of components and subsystems that make up the VPS is critical to the overall system operation.
Chirath Pathiravasam   +3 more
doaj   +1 more source

Fast and robust adaptive beamforming method based on complex-valued RBF neural network

open access: yesThe Journal of Engineering, 2019
The adaptive beamforming is one of the key techniques for array signal processing. However, the matrix inversion operation in the existing methods will cost a large amount of computational complexity, which results in poor real-time processing ability ...
Yuqing Li, Xiaopeng Yang, Feifeng Liu
doaj   +1 more source

An interactive web-based dashboard to track COVID-19 in real time

open access: yesLancet. Infectious Diseases (Print), 2020
E. Dong, H. Du, L. Gardner
semanticscholar   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

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