Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Correlation tracking via robust region proposals
Recently, correlation filter-based trackers have received extensive researching interest because of their simplicity and superior running speed. However, such trackers perform poorly when the target undergoes occlusion, viewpoint change, or other ...
Yuqi Han+4 more
doaj +1 more source
LIGHT-WEIGHT SENSOR PACKAGE FOR PRECISION 3D MEASUREMENT WITH MICRO UAVS E.G. POWER-LINE MONITORING [PDF]
The paper describes a new sensor package for micro or mini UAVs and one application that has been successfully implemented with this sensor package. It is intended for 3D measurement of landscape or large outdoor structures for mapping or monitoring ...
K.-D. Kuhnert, L. Kuhnert
doaj +1 more source
FAST-LIO: A Fast, Robust LiDAR-inertial Odometry Package by Tightly-Coupled Iterated Kalman Filter [PDF]
This paper presents a computationally efficient and robust LiDAR-inertial odometry framework. We fuse LiDAR feature points with IMU data using a tightly-coupled iterated extended Kalman filter to allow robust navigation in fast-motion, noisy or cluttered environments where degeneration occurs.
arxiv
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source
Modelling of continuously distributed target for bistatic synthetic aperture radar imaging
The point target model is widely used in the synthetic aperture radar (SAR) imaging simulation. Based on this model, the radar echo of a continuously distributed target can be expressed as the linear summation of the echo of many point targets which are ...
Xinliang Chen+3 more
doaj +1 more source
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten+10 more
wiley +1 more source
In remote sensing scene classification (RSSC), restrictions on real-time processing on power consumption, performance, and resources necessitate the compression of neural networks.
Jiahao Li+5 more
doaj +1 more source
SRARNet: A Unified Framework for Joint Superresolution and Aircraft Recognition
Aircraft recognition in high-resolution remote sensing images has rapidly progressed with the advance of convolutional neural networks (CNNs). However, the previous CNN-based methods may not work well for recognizing aircraft in low-resolution remote ...
Wei Tang+4 more
doaj +1 more source
Revolutionizing Supply Chain Management: Real-time Data Processing and Concurrency
In the contemporary business landscape, effective supply chain management (SCM) is paramount for organizations seeking to thrive amidst evolving market dynamics and heightened customer expectations.
Suwarna Shukla, Prabhneet Singh
semanticscholar +1 more source