Results 141 to 150 of about 41,831,427 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Real-Time Analysis of SARS-CoV-2-Induced Cytolysis Reveals Distinct Variant-Specific Replication Profiles. [PDF]

Viruses, 2023
Scheuermann SE, Goff K, Rowe LA, Beddingfield BJ, Maness NJ.   +4 more
europepmc   +2 more sources

Complete Worst-Case Execution Time Analysis of Straight-line Hard Real-Time Programs

, 1997
In this article, the problem of finding a tight estimate on the worst-case execution time (WCET) of a real-time program is addressed. The analysis is focused on straight-line code (i.e.
Real-time Programs, Peter Altenbernd, Straight-line Hard, Friedhelm Stappert   +3 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Tailoring confocal microscopy for real-time analysis of photosynthesis at single-cell resolution. [PDF]

Cell Rep Methods, 2023
Storti M, Hsine H, Uwizeye C, Bastien O, Yee DP, Chevalier F, Decelle J, Giustini C, Béal D, Curien G, Finazzi G, Tolleter D.   +11 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Real-Time Analysis of Round-based Distributed Algorithms

, 2010
Despite decades of research on networked fault-tolerant distributed systems, sound results on their real-time properties only exist for time-triggered synchronous systems: Given that classic distributed computing models are based on state machines with ...
Moser, Heinrich, Kößler, Alexander, Schmid, Ulrich   +2 more
core   +2 more sources

LEAN: Real-Time Analysis of Resistance Training Using Wearable Computing. [PDF]

Sensors (Basel), 2023
Coates W, Wahlström J.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Algorithm for real-time analysis of intracoronary electrocardiogram. [PDF]

Front Cardiovasc Med, 2022
Bigler MR, Kieninger-Gräfitsch A, Waldmann F, Seiler C, Wildhaber R.   +4 more
europepmc   +1 more source