Results 71 to 80 of about 41,831,427 (302)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Secondary Electrospray Ionization Mass Spectrometry for Volatile Analysis: Current Challenges and Emerging Solutions

Analytica
Secondary electrospray ionization mass spectrometry (SESI-MS) has emerged as a powerful technique for the real-time, non-invasive analysis of volatile organic compounds (VOCs) in complex matrices, such as exhaled breath and microbial volatilomes. However,
Diego García-Gómez, Ana Ballester-Caudet, María Esther Fernández Laespada   +2 more
doaj   +1 more source

Real-time DNA microarray analysis [PDF]

Nucleic Acids Research, 2009
We present a quantification method for affinity-based DNA microarrays which is based on the real-time measurements of hybridization kinetics. This method, i.e. real-time DNA microarrays, enhances the detection dynamic range of conventional systems by being impervious to probe saturation in the capturing spots, washing artifacts, microarray spot-to-spot
Hassibi, Arjang, Vikalo, Haris, Riechmann, José Luis, Hassibi, Babak   +3 more
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Ultrafast Detection of Arsenic Using Carbon-Fiber Microelectrodes and Fast-Scan Cyclic Voltammetry

Micromachines
Arsenic contamination poses a significant public health risk worldwide, with chronic exposure leading to various health issues. Detecting and monitoring arsenic exposure accurately remains challenging, necessitating the development of sensitive detection
Noel Manring, Miriam Strini, Gene Koifman, Jonathan Xavier, Jessica L. Smeltz, Pavithra Pathirathna   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Case study: software solution for vehicle license plate detection

Известия Томского политехнического университета: Промышленная кибернетика
This article illustrates the development of a software product aimed at automated recognition and classification of vehicle license plates using camera video images.
Semen M. Levin, Artem E. Tikhonov
doaj   +1 more source

Qualification of an Ultrasonic Instrument for Real-Time Monitoring of Size and Concentration of Nanoparticles during Liquid Phase Bottom-Up Synthesis

Applied Sciences, 2018
Both in design and production of nanoparticles and nanocomposites it is of vital importance to have information about their size and concentration. During the formation of nanoparticles, real-time monitoring of particle size and concentration during ...
Gert Jan van Groenestijn, Nicole Meulendijks, Renz van Ee, Arno Volker, Paul van Neer, Pascal Buskens, Cédric Julien, Marcel Verheijen   +7 more
doaj   +1 more source

Frontiers of Real-Time Data Analysis [PDF]

Journal of Economic Literature, 2008
In the past ten years, researchers have explored the impact of data revisions in many different contexts. Researchers have examined the properties of data revisions, how structural modeling is affected by data revisions, how data revisions affect forecasting, the impact of data revisions on monetary policy analysis, and the use of real-time data in ...
openaire   +3 more sources