Results 101 to 110 of about 238,739 (317)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Enhanced tracking wall: A real-time computing method for needle injection on haptic simulators

open access: green, 2020
Ma de Los Angeles Alamilla-Daniel   +2 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Portfolio Optimization: A Neurodynamic Approach Based on Spiking Neural Networks

open access: yesBiomimetics
Portfolio optimization is fundamental to modern finance, enabling investors to construct allocations that balance risk and return while satisfying practical constraints.
Ameer Hamza Khan   +2 more
doaj   +1 more source

Real-Time Automated Classification of Sky Conditions Using Deep Learning and Edge Computing [PDF]

open access: gold, 2021
Joby M. Prince Czarnecki   +4 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

IoT- Enabled Firmness Grades of Tomato in Cold Supply Chain Using Fusion of Whale Optimization Algorithm and Extreme Learning Machine

open access: yesIEEE Access
The assessment of tomato firmness is pivotal in determining optimal harvest time, evaluating shelf life, and gauging ripeness. This attribute plays a crucial role in guiding the distribution and transportation processes.
Ali Haider   +6 more
doaj   +1 more source

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