Results 101 to 110 of about 244,199 (317)

I2OT-EC: A Framework for Smart Real-Time Monitoring and Controlling Crude Oil Production Exploiting IIOT and Edge Computing [PDF]

, 2023
Hazem Ramzey, Mahmoud Badawy, Mostafa A. Elhosseini, Adel A. Elbaset   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Reconciling fault-tolerant distributed algorithms and real-time computing. [PDF]

Distrib Comput, 2014
Moser H, Schmid U.
europepmc   +1 more source

Hepatocellular adenoma: comparison between real-time contrast-enhanced ultrasound and dynamic computed tomography [PDF]

, 2016
Wei Wang, Jin-Ya Liu, Yang Zheng, Yuefeng Wang, Shunli Shen, Fenglian Yi, Yang Huang, Erjiao Xu, Xiaoyan Xie, Ming‐De Lu, Zhu Wang, Li‐Da Chen   +11 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Portfolio Optimization: A Neurodynamic Approach Based on Spiking Neural Networks

Biomimetics
Portfolio optimization is fundamental to modern finance, enabling investors to construct allocations that balance risk and return while satisfying practical constraints.
Ameer Hamza Khan, Aquil Mirza Mohammed, Shuai Li   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

IoT- Enabled Firmness Grades of Tomato in Cold Supply Chain Using Fusion of Whale Optimization Algorithm and Extreme Learning Machine

IEEE Access
The assessment of tomato firmness is pivotal in determining optimal harvest time, evaluating shelf life, and gauging ripeness. This attribute plays a crucial role in guiding the distribution and transportation processes.
Ali Haider, Rafaqat Kazmi, Teg Alam, Rab Nawaz Bashir, Haitham Nobanee, Amjad Rehman Khan, Aqsa   +6 more
doaj   +1 more source

Noise2Filter: fast, self-supervised learning and real-time reconstruction for 3D computed tomography

, 2020
Marinus J. Lagerwerf, Allard A. Hendriksen, Jan‐Willem Buurlage, Kees Joost Batenburg   +3 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source