Implementation of a general real-time visual anomaly detection system via soft computing [PDF]
, 2004 Jesús Domínguez +2 more
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Reconciling fault-tolerant distributed algorithms and real-time computing. [PDF]
Distrib Comput, 2014 Moser H, Schmid U.
europepmc +1 more source
743 Importance of focal zone position for detection of apical ischemia by my ocardial real-time perfusion stress echocardiography compared with 99mTc-sestamibi single-photon emission computed tomography [PDF]
, 2005 Petri Gudmundsson +4 more
openalex +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Consciousness qua Mortal Computation [PDF]
arXivComputational functionalism posits that consciousness is a computation. Here we show, perhaps surprisingly, that it cannot be a Turing computation. Rather, computational functionalism implies that consciousness is a novel type of computation that has recently been proposed by Geoffrey Hinton, called mortal computation.
arxiv
Integrated Electroanatomic Mapping With Three-Dimensional Computed Tomographic Images for Real-Time Guided Ablations [PDF]
, 2006 Jun Dong +10 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Computing during supply voltage switching in DVS enabled real-time processors [PDF]
, 2006 C. Duan, Sunil P. Khatri
openalex +1 more source