Results 111 to 120 of about 3,329,473 (267)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Real-time time-varying economic nonlinear model predictive control for wind turbines

International Journal of Electrical Power & Energy Systems
Economic nonlinear model predictive control is a great choice to tackle the control issues appearing in the current wind energy industry. In this paper, instead of generator power, aerodynamic power is employed in the economic cost function to establish ...
Mohammad Soleymani, Nooshin Bigdeli, Mehdi Rahmani   +2 more
doaj   +1 more source

Contactless Inductive Flow Tomography for Real-Time Control of Electromagnetic Actuators in Metal Casting. [PDF]

Sensors (Basel), 2022
Glavinić I, Galindo V, Stefani F, Eckert S, Wondrak T.   +4 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Real-Time Control Technology for a Bio-Liquor Circulation System in a Swine Barn with Slurry Pit: Pilot Scale Study. [PDF]

Animals (Basel), 2022
Kim S, Shim S, Won S, Kwag J, Ra C.
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Towards Tomography-Based Real-Time Control of Multiphase Flows: A Proof of Concept in Inline Fluid Separation. [PDF]

Sensors (Basel), 2022
Garcia MM, Sattar MA, Atmani H, Legendre D, Babout L, Schleicher E, Hampel U, Portela LM.   +7 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

Advanced Science
Control theory underpins the stabilization of dynamic systems, including cardiac tissue, where disruptions in electrical conduction cause arrhythmias.
Shanliang Deng, Niels Harlaar, Juan Zhang, Sven O. Dekker, Nina N. Kudryashova, Huiling Zhou, Cindy I. Bart, TianYi Jin, Georgy Derevyanko, Willem vanDriel, Alexander V. Panfilov, René H. Poelma, Antoine A. F. deVries, GuoQi Zhang, Tim De Coster, Daniël A. Pijnappels   +15 more
doaj   +1 more source

Real-Time Control of a Multi-Degree-of-Freedom Mirror Myoelectric Interface During Functional Task Training. [PDF]

Front Neurosci, 2022
Sarasola-Sanz A, López-Larraz E, Irastorza-Landa N, Rossi G, Figueiredo T, McIntyre J, Ramos-Murguialday A.   +6 more
europepmc   +1 more source