Results 131 to 140 of about 5,876,409 (379)

Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells

Drug Design, Development and Therapy, 2016
NamHuk Baek,1,* Ok Won Seo,1,* Jaehwa Lee,1 John Hulme,2 Seong Soo A An2 1Department of Research and Development, NanoEntek Inc., Seoul, 2Department of BioNano Technology, Gachon University, Gyeonggi-do, Korea *These authors contributed equally to this
Baek NH, Seo OW, Lee J, Hulme J, An SSA
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

RetComm 1.0: Real Time Condition Monitoring of Rotating Machinery Failure

MATEC Web of Conferences, 2018
The breakdown of motor proves to be very expensive as it increases downtime on the machines. Development of cost-effective and reliable condition monitoring system for the protection of motors to avoid unexpected breakdowns is necessary.
Hong Lee Chun, Mahamad Abd Kadir, Saon Sharifah   +2 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Attention focussing and anomaly detection in real-time systems monitoring [PDF]

In real-time monitoring situations, more information is not necessarily better. When faced with complex emergency situations, operators can experience information overload and a compromising of their ability to react quickly and correctly. We describe an
Chien, Steve A., Doyle, Richard J., Fayyad, Usama M., Porta, Harry J.   +3 more
core   +1 more source

Aggregating multiple body sensors for analysis in sports [PDF]

, 2008
Real time monitoring of the wellness of sportspersons, during their sporting activity and training, is important in order to maximise performance during the sporting event itself and during training, as well as being important for the health of the ...
Diamond, Dermot, Kelly, Philip, Lau, King-Tong, Moran, Kieran, Morris, Deirdre, Moyna, Niall, O'Connor, Noel E., Smeaton, Alan F., Zhang, Ke   +8 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Real-Time Exam Monitoring

International Journal of Advanced Research in Science, Communication and Technology
With the rapid expansion of online learning platforms and remote assessments, ensuring academic integrity during examinations has become a significant challenge. Traditional human proctoring methods have limitations in scalability, accuracy, and cost-effectiveness.
null Om Malekar, null Aditya Karale, null Pravin Pawara, null Reena Gharat   +3 more
openaire   +1 more source