Results 141 to 150 of about 21,518,469 (313)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Library for fMRI Real-Time Processing Systems in Python (RTPSpy) With Comprehensive Online Noise Reduction, Fast and Accurate Anatomical Image Processing, and Online Processing Simulation. [PDF]

Front Neurosci, 2022
Misaki M, Bodurka J, Paulus MP.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Radar real-time image processing for machine perception

, 2019
The paper reviews real-time image processing techniques for machine perception with a specific focus on radar image processing for autonomous vehicles.
Sergio Saponara, Saponara S.
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Reconfigurable FPGAs for Real-time Image Processing in Space

, 2002
Programmable logic offers an efficient solution for the performance and flexibility required by real time image processing systems. Application Specific Integrated Circuit (ASIC) devices could provide such performance, but the lack of flexibility for ...
Dawood, Anwar S., Dawood, Anwar, Visser, Stephen, Williams, John A., Visiter, Stephen J., Williams, John   +5 more
core   +1 more source

A multi-target drug design method based on target feature fusion

BMC Bioinformatics
Background Targeted drugs are medications designed to treat diseases by targeting specific sites on cancerous or diseased cells. Multi-target drugs can target multiple protein sites to treat diseases, improving therapeutic efficiency, but are more ...
Haoran Liu, Xiaoli Lin, Jing Hu, Xiaolong Zhang   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Real-time high-resolution omnidirectional imaging platform for drone detection and tracking

Drones have become steadily affordable, which raises privacy and security concerns as well as interest in drone detection systems. On the other hand, drone detection is a challenging task due to small dimensions of drones, difficulty of long-distance ...
Demir, Bilal, Thiran, Jean-Philippe, Ott, Beat, Nurlu, Gokcen, Popovic, Vladan, Leblebici, Yusuf, Ergunay, Selman, Wellig, Peter   +7 more
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source