Results 181 to 190 of about 21,518,469 (313)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Real-time processing of high-throughput quantitative phase microscopy data using a Jetson Orin Nano. [PDF]

Biophotonics Discov
Wang W, Highland RE, Fan J, Miller DA, Wax A.   +4 more
europepmc   +1 more source

Real-Time Processing Library for Open-Source Hardware Biomedical Sensors. [PDF]

Sensors (Basel), 2018
Molina-Cantero AJ, Castro-García JA, Lebrato-Vázquez C, Gómez-González IM, Merino-Monge M.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A Deep-Learning Empowered, Real-Time Processing Platform of fNIRS/DOT for Brain Computer Interfaces and Neurofeedback. [PDF]

IEEE Trans Neural Syst Rehabil Eng
Xia Y, Chen J, Li J, Gong T, Vidal-Rosas EE, Loureiro R, Cooper RJ, Zhao H.   +7 more
europepmc   +1 more source

Deficits in the Use of Verb Bias Information in Real-Time Processing by College Students With Developmental Language Disorder. [PDF]

J Speech Lang Hear Res, 2019
Hall JE, Owen Van Horne A, McGregor KK, Farmer TA.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Hardware Accelerator for Real-Time Processing Platforms Used in Synthetic Aperture Radar Target Detection Tasks. [PDF]

Micromachines (Basel)
Zhang Y, Tang Y, Cao Y, Yu Z.
europepmc   +1 more source

A Visual Cortex-Inspired Imaging-Sensor Architecture and Its Application in Real-Time Processing. [PDF]

Sensors (Basel), 2018
Wei H, Wang L.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source