Results 131 to 140 of about 34,578,248 (345)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Scalability in Real-Time Systems

, 1996
The number and complexity of applications that run in real-time environments have posed demanding requirements on the part of the real-time system designer. It has now become important to accommodate the application complexity at early stages of the design cycle.
openaire   +3 more sources

Comment on Novozhilova et al. More Capable, Less Benevolent: Trust Perceptions of AI Systems across Societal Contexts. Mach. Learn. Knowl. Extr. 2024, 6, 342–366

Machine Learning and Knowledge Extraction
The referenced article [...]
Robertas Damaševičius
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

MDARTS: A Multiprocessor Database Architecture for Real-Time Systems

, 2007
Some of the advanced real-time systems being proposed, such as the Next Generation Workstation/Machine Controller (NGC) for automated factories, require a built-in database to support concurrent data access and provide well-defined interfaces between ...
Real-Time Computing Laboratory
core  

Toward Software-Defined Vehicles: From Model-Based Engineering to Virtualization-Based Deployment

IEEE Access
The automotive industry is moving towards software-defined vehicles, where software shapes the car’s features and user experience. Unlike traditional vehicles that rely on multiple separate computing units with tightly coupled software, the new ...
Fengjunjie Pan, Markus Rickert, Tobias Betz, Long Wen, Jianjie Lin, Nenad Petrovic, Markus Lienkamp, Alois Knoll   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Uniprocessor scheduling of real-time synchronous dataflow tasks

, 2018
The synchronous dataflow graph (SDFG) model is widely used today for modeling real-time applications in safety-critical application domains. Schedulability analysis techniques that are well understood within the real-time scheduling community are applied
Pontus Ekberg, Singh, Abhishek, Sanjoy Baruah, Ekberg, Pontus,, Baruah, Sanjoy, Abhishek Singh   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source