Results 71 to 80 of about 6,983,756 (292)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Testing multi input-output real-time systems (Extended version) [PDF]

open access: yes, 2005
In formal testing, the assumption of input enabling is typically made. This assumption requires all inputs to be enabled anytime. In addition, the useful concept of quiescence is sometimes applied. Briefly, a system is in a quiescent state when it cannot
Brandan Briones, Laura, Brinksma, Ed
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Real time systems and public information [PDF]

open access: yes
Using computer technology in future public information ...
Churchman, C. W.
core   +1 more source

Automated Real-Time Testing (ARTT) for Embedded Control Systems (ECS) [PDF]

open access: yes, 2001
Developing real-time automated test systems for embedded control systems has been a real problem. Some engineers and scientists have used customized software and hardware as a solution, which can be very expensive and time consuming to develop.
Hawkins, Jon   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Event-Based Robotic Grasping Detection With Neuromorphic Vision Sensor and Event-Grasping Dataset

open access: yesFrontiers in Neurorobotics, 2020
Robotic grasping plays an important role in the field of robotics. The current state-of-the-art robotic grasping detection systems are usually built on the conventional vision, such as the RGB-D camera. Compared to traditional frame-based computer vision,
Bin Li   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Scalable Δ -AGC Logic for Enhanced Electromechanical Oscillation Damping in Modern Power Systems With Utility-Scale Photovoltaic Generators

open access: yesIEEE Access
Power systems with utility-scale solar photovoltaic (PV) can significantly influence the operating points (OPs) of synchronous generators, particularly during periods of high solar PV generation.
Rajan Ratnakumar   +1 more
doaj   +1 more source

Home - About - Disclaimer - Privacy