Results 131 to 140 of about 19,456,308 (297)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hypercomplex Numbers—A Tool for Enhanced Efficiency and Intelligence in Digital Signal Processing
MathematicsMathematics is the wide-ranging solid foundation of the engineering sciences which ensures their progress by providing them with its unique toolkit of rules, methods, algorithms and numerical systems.
Zlatka Valkova-Jarvis +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Desde el Jardín de Freud, 2012 Desde la primera crisis de la institución analítica en 1953, Lacan se da cuenta de que la transmisión del psicoanálisis es fundamental para su supervivencia; por ello, a lo largo de su enseñanza, reflexionará y construirá los medios de formación de ...
Isabelle Morin
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
La República de los psicoanalistas
Desde el Jardín de Freud, 2012 En la comunidad analítica se ha trabajado la función del síntoma en la construcción del lazo social. El tema central del presente artículo pretende abrir la reflexión en torno al aporte de Lacan en los últimos años de su enseñanza, con respecto a la ...
Ramón Menéndez Pla
doaj
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
La segregación del psicoanalista
Desde el Jardín de Freud, 2013 Tomando como punto de partida las observaciones lacanianas sobre la segregación en su “Discurso de clausura de las jornadas sobre psicosis infantil”, este artículo se propone elucidar en qué forma Lacan introduce la cuestión; si la segregación es una ...
Marie-Jean Sauret
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source