Results 41 to 50 of about 9,824,063 (250)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
RTXlet: uma abordagem de tempo real para aplicações de tv digital baseadas em Xlets [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia ElétricaEste trabalho propõe uma nova abordagem para aplicações de TV Digital.
Hartke Neto, Roberto
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Real Cost of HLB in Florida
I estimated the cultural cost per acre of managing HLB in orange citrus groves in Florida to be $663, which represents a 67% increase compared to pre-HLB levels.
Ariel Singerman
doaj
Abolitionist memory work in The Real Cost of Prisons Comix
In this article, we identify the comics of the Real Cost of Prisons Project as graphic memory work that denaturalises ‘penal common sense’ and engages in graphic witnessing.
Duygu Erbil, Eamonn Connor
doaj +1 more source
Moving and handling in the community: The real cost of an informal carer
MOVING AND HANDLING IN THE COMMUNITY: THE REAL COST OF AN INFORMAL CARER Introduction. Musculoskeletal disorders (MSDs) are the leading cause of work disability, sickness absence from work, and loss of productivity in healthcare across all the European
Jamie Wyton
doaj +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The application of the emerging hybrid analog–digital architecture for future millimeter‐wave communications has attracted significant attention. Although this architecture can reduce the hardware cost and power consumption considerably, the high ...
Changzan Liu, Yan Zhou, Bo Dang
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

