Results 41 to 50 of about 269,678 (255)
IMPACT OF EXCHANGE RATE VOLATILITY ON MANUFACTURING OUTPUT IN NIGERIA
Exchange rate volatility has remained a major challenge for Nigeria’s economic stability and industrial growth over the past decade. The manufacturing sector, which should serve as a driver of structural transformation, has been particularly vulnerable ...
Taiwo A. Muritala
doaj +1 more source
Real Exchange Rates, Valuation Effects and Growth in Emerging Markets [PDF]
We compare the relationship between net capital inflows, real exchange rate movements and growth for twenty emerging markets and twelve developed countries over the period 1985–2004. In developed countries low real exchange rates are associated with faster growth, but in emerging markets depreciations depress growth, even outside crisis periods, and ...
Michael Bleaney, +1 more
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Tourism industry: Role of the real effective exchange rate
This paper aims to evaluate an econometric model of equilibrium for the Bulgarian foreign tourism industry. The main microeconomic assumptions of the model are the existence of identical consumers, identical composite tourism industry product and ...
Gancho Todorov Ganchev
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
بررسی عوامل تعیین کننده نرخ ارز موثر واقعی در ایران با استفاده از رگرسیون فازی [PDF]
نرخ ارز نقش اساسی در تعیین درجه رقابت بینالمللی و وضعیت اقتصاد داخلی دارد، لذا شناسایی عوامل موثر بر آن میتواند در سیاستگذاریهای تجاری مفید باشد. با این وجود، اثر متغیرها بر نرخ ارز اغلب با ابهام و نااطمینانی همراه است، لذا استفاده از رگرسیون فازی ...
حسین اصغرپور +2 more
doaj
The aim of this study is to examine empirically the validity of PPP in the context of unit root tests based on linear and non-linear models of the real effective exchange rate of Argentina, Brazil, Chile, Colombia, Mexico, Peru and Venezuela.
Claudio Roberto Fóffano Vasconcelos +1 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source

