Results 41 to 50 of about 16,852,075 (304)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Real Exchange Rates in Developing Countries: Are Balassa-Samuelson Effects Present? [PDF]

open access: yesIMF Staff Papers, 2004
There is little empirical research on whether Balassa-Samuelson effects can explain the long-run behavior of real exchange rates in developing countries. This paper presents new evidence on this issue based on a panel data sample of 16 developing countries. The paper finds that the traded-nontraded productivity differential is a significant determinant
Ehsan U. Choudhri, Mohsin S. Khan
openaire   +2 more sources

IMPACT OF EXCHANGE RATE VOLATILITY ON MANUFACTURING OUTPUT IN NIGERIA

open access: yesGusau Journal of Accounting and Finance
Exchange rate volatility has remained a major challenge for Nigeria’s economic stability and industrial growth over the past decade. The manufacturing sector, which should serve as a driver of structural transformation, has been particularly vulnerable ...
Taiwo A. Muritala
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Real Exchange Rate Effects of Fiscal Policy [PDF]

open access: yes, 1984
This paper develops a framework for analyzing the effects of fiscal policy on the real exchange rate. The short-run impact of various types of fiscal measures are considered as well as the dynamics of adjustment to long-run steady states. The analysis and related simulations suggest that the effect of fiscal policy changes on the real exchange rate can
Sachs, Jeffrey D., Wyplosz, Charles
openaire   +2 more sources

Real Exchange Rates, Valuation Effects and Growth in Emerging Markets [PDF]

open access: yesOpen Economies Review, 2009
We compare the relationship between net capital inflows, real exchange rate movements and growth for twenty emerging markets and twelve developed countries over the period 1985–2004. In developed countries low real exchange rates are associated with faster growth, but in emerging markets depreciations depress growth, even outside crisis periods, and ...
Michael Bleaney,   +1 more
openaire   +3 more sources

Tourism industry: Role of the real effective exchange rate

open access: yesTourism & Management Studies, 2014
This paper aims to evaluate an econometric model of equilibrium for the Bulgarian foreign tourism industry. The main microeconomic assumptions of the model are the existence of identical consumers, identical composite tourism industry product and ...
Gancho Todorov Ganchev
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Determinants of the euro real effective exchange rate: a BEER/PEER approach [PDF]

open access: yes
This paper presents an empirical analysis of the medium-term determinants of the euro effective exchange rate. The empirical analysis builds on synthetic quarterly data from 1975 to 1998, and derives a Behavioural Equilibrium Exchange Rate (BEER) and a ...
Bernd Schnatz   +2 more
core   +2 more sources

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