Results 41 to 50 of about 11,791,792 (307)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Real effective exchange rate-indicator of Serbia's competitiveness [PDF]
Ekonomski Pogledi, 2015 Current business conditions imply intensive relations and interdependence between national economies at the global level. In such economic environment, it is natural to give high importance to international economic relations, and to put forward the ...
Makivić Ranko
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Are Asian real exchange rates stationary? [PDF]
Economics Letters, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Liew, Venus Khim-Sen +2 more
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Movement of the real effective exchange rate of the convertible mark [PDF]
BankarstvoIn the research, we evaluated the equilibrium real effective exchange rate of the convertible mark and identified a significant deviation of the real effective exchange rate of the convertible mark concerning the equilibrium level, especially during the ...
Jović Dragan
doaj +1 more source
Long Memory and Parity Reversion in Real Exchange Rate
Malaysian Management Journal, 2020 This paper examines the post Bretton Woods experience of the Malaysian Ringgit. In this period, Malaysia moved from a managed to a floating exchange rate environment.We examine persistence in real exchange rates by estimating fractionally integrated ...
Abd. Ghafar Ismail, Wahi Ismail
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Nonlinear effects of real exchange rate uncertainty on oil and non-oil economic growth in IRAN: GARCH-M approach [PDF]
Faslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2014 In recent years, researchers have been increasingly noticed economic growth and its determinants. Exchange rate and its volatility are important factors in determining a country's economic growth. Various studies in this regard have shown contradictory
Mostafa Mobini Dehkordi +1 more
doaj