Results 101 to 110 of about 471,485 (276)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Real-time interpolation of streaming data

Computer Science, 2020
One of the key elements of real-time $C^1$-continuous cubic spline interpolation of streaming data is an estimator of the first derivative of the interpolated function that is more accurate than the ones based on finite difference schemas.Two such greedy look-ahead heuristic estimators (denoted as MinBE and MinAJ2) based on Calculus of Variations are ...
openaire   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Multi-Aspect Interpolation Method for SAR Complex Images of Typical Aircraft Target Using Multi-Aspect Scattering Information Complex Generative Adversarial Network

Remote Sensing
Due to the huge differences in Synthetic Aperture Radar (SAR) image features of the same target under different observing aspects, the demand for constructing multi-aspect SAR datasets of various typical targets is becoming increasingly urgent with the ...
Shixin Wei, Bing Han, Jiayuan Shen, Jiaxin Wan, Yugang Feng, Qianyue Xue   +5 more
doaj   +1 more source

Real interpolation for non-distant marcinkiewicz spaces

Revista Matemática Complutense, 2001
Lorentz-Zygmund spaces \(L^{p,r}(\log L)^\alpha\), introduced by \textit{C. Bennett} and \textit{K. Rudnick} in [Diss. Math. 175, 67 p. (1980; Zbl 0456.46028)], were generalized to new spaces \(L_{p,\alpha,E}\) on \((0,1)\) by the author in [J. Anal. Math.
openaire   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

2D and 3D Optical Flow Based Interpolation of the 4DCT ImageSequences in the External Beam Radiotherapy

Frontiers in Biomedical Technologies, 2015
Purpose: Although in the external beam radiotherapy tumor motionis a crucial and challenging issue due to respiration  motion, temporal changes in anatomy during imaging cause considerable problems.
Payam Samadi-Miyandoab, AhmadEsmaili Torshabi, Saber Nankali   +2 more
doaj  

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source