Results 91 to 100 of about 348,152 (265)

A NOVEL HYBRIDIZED ALGORITHM FOR REDUCTION OF REAL POWER LOSS

International Journal of Research -GRANTHAALAYAH, 2017
This paper proposes Hybridization of Gravitational Search algorithm with Simulated Annealing algorithm (HGS) for solving optimal reactive power problem. Individual position modernize strategy in Gravitational Search Algorithm (GSA) may cause damage to the individual position and also the local search capability of GSA is very weak.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Towards the Detection of Unobservable Losses in Real-Time Communications

2024 IEEE 30th International Symposium on Local and Metropolitan Area Networks (LANMAN)
Packet loss, an omnipresent issue that degrades the QoE in Real-time Transport Protocol (RTP)-based real-time communications (RTC) applications, serves as a pivotal indicator for gauging network performance. Conventionally, loss detection hinges on sequence number irregularities. However, many contemporary applications incorporate customized mechanisms
Song, Tailai, Garza, Paolo, Meo, Michela, Munafo, Maurizio Matteo   +3 more
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Minimizing Real Power Losses Via Optimal Reactive Power Allocation and Distributed Generation Using Grey Wolf Optimizer

Journal of Engineering and Sustainable Development
An emphasis is placed on the optimal location and sizing of distributed generation and reactive power compensation to minimize real power loss in the Radial Distribution Network.
Bahaa Hussein Al IGEB, Petr P. Oschepkov , Mazin T Muhssin, Murtadha AL-KAABI, Ali abdulazeez, Saad K. Khalaf Khalaf   +5 more
doaj   +1 more source

Assessment of water loss level on the example of selected distribution systems

E3S Web of Conferences, 2018
One of the major problems of waterworks is the excessive failure of distribution systems and associated water leaks. Water losses in water supply networks and systems are often a very high percentage of water supplied into the network.
Ociepa Ewa, Molik Robert, Lach Joanna
doaj   +1 more source

REAL POWER LOSS REDUCTION BY ENRICHED GENETIC ALGORITHM

International Journal of Research -GRANTHAALAYAH, 2017
In this paper, Enriched Genetic Algorithm (EGA) utilized to solve reactive power optimization problem. In the proposed algorithm Stochastic Universal Selection (SS) is utilized to improve the selection procedure. The selection method in Genetic algorithm (GA) plays a significant role in the runtime to get the optimized solution as well as in the ...
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source