Results 41 to 50 of about 2,325,720 (350)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Real Options

open access: yes, 2015
When (real sector) investment projects are characterized by a substantial degree of uncertainty and irreversibility, and carry some flexibility in the timing of execution, they are conceptually analogous to financial options. As such, the concepts and valuation models developed in the financial options literature can also be applied to characterize and
Engelen, P.J., Cassimon, Danny
openaire   +3 more sources

Evaluation method of investment based on real option analysis [PDF]

open access: yesЭкономика региона, 2013
The article describes the advantages and the procedurefor applying thetheory ofreal options analysis to theevaluation of investment projects. Also describes the disadvantages of traditional methods and attempt to apply the method of real options to the ...
Evgeniy Anatolyevich Malyshev   +1 more
doaj   +1 more source

Operational asset replacement strategy : a real options approach [PDF]

open access: yes, 2009
This article analyses the problem of replacement by investigating the optimal moment of investment replacement in a given tax environment with a given depreciation policy.
Duque, João, Zambujal, João
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Real options valuation of franchise territorial exclusivity

open access: yesCogent Business & Management, 2017
With the maturity of the franchise system, franchisors have to look for new markets to capitalize constantly. This continuing expansion comes at the expense of the existing franchise establishments, as it could lead to territorial encroachment.
Lukito Adi Nugroho
doaj   +1 more source

Real Options Based Analysis for Supply Chain Management [PDF]

open access: yesInternational Journal of Industrial Engineering and Production Research, 2022
Supply chain management is one of the requirements for achieving economic growth in any supply chain. If managers' decisions are optimally allocated, it will be possible for companies and industries with a competitive and profitable advantage to grow and
Abolfazl Khatti Dizabadi   +2 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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