Results 111 to 120 of about 29,012,891 (356)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Advanced Biofuel Production in Louisiana Sugar Mills: an Application of Real Options Analysis [PDF]
In order to more fully study the risks and uncertainty involved in cellulosic ethanol production, we examine a simulated plant in South Louisiana using Real Options Analysisreal options, risk, uncertainty, cellulosic ethanol, energy cane, sorghum ...
Salassi, Michael E. +3 more
core
A real options analysis of Australian wheat production under climate change
, 2016 type="main" xml:id="ajar12104-abs-0001"> A significant portion of the world's agricultural systems currently operate at the extreme end of the climate conditions that are considered to be suitable for crop and livestock production. Under these conditions,
Todd Sanderson +3 more
semanticscholar +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Real Options Accounting and Uncertainty
, 2005 The discounted cash flow or net present value model in the corporate valuation and decision-making has defects because of un-flexibility. The real options model gets over these faults because it can deal with uncertainty in the corporate business process.
上野, 清貴
core
Transport, 2013 Countries around the world have welcomed Public Private Partnerships (PPPs) as an alternative to finance infrastructure. For strategic projects with high demand uncertainty, a government may decide to provide a concessionaire with a Minimum Revenue ...
Nakhon Kokkaew, Nicola Chiara
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Long run value stabilization in a real options perspective [PDF]
The present value of growth opportunities with stable long run value and decreasing investment cost is addressed in a real options perspective. The model is solved in terms of closed form solutions, and a duality between elementary real options of ...
A. Mantovi
core
Real options and risk aversion
In the standard real options approach to investment under uncertainty, agents formulate optimal policies under the assumptions of risk neutrality or complete financial markets.
Morellec, Erwan, Hugonnier, Julien N.
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source