Results 91 to 100 of about 7,102,753 (249)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Memorias de la Real Academia de Ciencias de Madrid

Na portada: 3ª Serie. Ciencias naturales. Tomo III. 1ª ParteAntepEsc. real xil.
Real Academia de Ciencias de Madrid
core  

Action Plan

, 2012
Sociology Department's Action Plan - Academic Program ReviewSociology Department's Action PlanSociology Department - Academic Program ...
Sociology Department's Action Plan, Academic Program Review
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Comparison of Hoteling Cost of Global Surgery with Real Cost in Isfahan Public Hospitals, 2012

Journal of Evidence Based Health Policy, Management & Economics, 2017
Background: Paying for the global surgery is one of the prospective payment methods in which service providers receive their service costs according to a preset table.
AmirHosein Fattahpour, Reza Ebrahimi Dourcheh, Mohsen Rahimi, Noora Rafiee   +3 more
doaj  

Reglamento provisional ... para el establecimiento y gobierno del Colegio Real y Militar de Caballeros Guardias Marinas.

Port. con esc.
Colegio Real y Militar de Caballeros Guardias Marinas
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Manifiesto de los procedimientos del Consejo Real en los gravísimos sucesos ocurridos desde octubre del año próximo pasado, impreso de orden del mismo Supremo Tribunal

Lugar deducido de la sede del imp.Sign.: 1-14\4, 15\2Port. con esc.
Consejo Real de Castilla
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Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source