Results 121 to 130 of about 13,847,606 (337)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Retirement Annuity Design in an Inflationary Climate [PDF]

This paper examines the tilt and risk-return characteristics of real retirement incomes provided by variable annuities tied to bills, long-term bonds, stocks and a mixed portfolio which combines all three.
James E. Pesando, Zvi Bodie
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Assessing Functional Efficiency of Courtyards [PDF]

صفه, 2016
This paper uses the space syntax methodology to assess the efficiency of the courtyard in eight traditional house designs. Each of the houses selected for this study boasts a different plan composition in connection with the location and number of the ...
Yaghoob Peyvastehgar, Aliakbar Heidari, Maryam Kiaee   +2 more
doaj  

Brazil's Incomplete Stabilization and Reform [PDF]

macroeconomics, stabilization, international, reform, Brazil, Real Plan, structural reform ...
Rudiger Dornbusch
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Plan de prevención de la alergia al látex en el área sanitaria de Ciudad Real

Medicina y Seguridad del Trabajo, 2008
Durante el año 2004 se instaura un Plan de Prevención de Alergia al Látex en el Área Sanitaria de Ciudad Real para cumplir con el Plan de Calidad del Servicio de Salud de Castilla la Mancha. Este plan se desarrollaría en tres vías de actuación y de forma
Carmen Marroquí López-Clavero, Isabel Solano Herrera, Mª Isabel Riesco García   +2 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A comparison allocation of labor qualification on real, plan, and regulation calculation using resource-leveling method

Jurnal Sistem dan Manajemen Industri
Labor is a crucial resource in industrial construction projects. A common issue is the uneven number of laborers who are overallocated. This study uses the resource-leveling method to compare and determine the optimal number of labor and project duration
Izmanaya Avril Servanty, I Nyoman Dita Pahang Putra, Robby Soetanto   +2 more
doaj   +1 more source

Future Productivity Growth in Canada and Implications for the Canada Pension Plan [PDF]

This is organized into three main parts. The first section provides a perspective on future productivity growth in Canada. It discusses key productivity concepts, looks at current productivity trends, examines the forces affecting future productivity ...
Andrew Sharpe
core