Results 91 to 100 of about 118,453 (329)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Spaces of equivariant algebraic maps from real projective spaces into complex projective spaces

open access: yes, 2011
We study the homotopy types of certain spaces closely related to the spaces of algebraic (rational) maps from the $m$ dimensional real projective space into the $n$ dimensional complex projective space for $2\leq m\leq 2n$ (we conjecture this relation to be a homotopy equivalence). In an earlier article we proved that the homotopy types of the terms of
Kozlowski, Andrzej, Yamaguchi, Kohhei
openaire   +2 more sources

WDVV-Type Relations for Welschinger's Invariants: Applications

open access: yes, 2019
We first recall Solomon's relations for Welschinger's invariants counting real curves in real symplectic fourfolds, announced in \cite{Jake2} and established in \cite{RealWDVV}, and the WDVV-style relations for Welschinger's invariants counting real ...
Chen, Xujia, Zinger, Aleksey
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

SOCIO-PSYCHOLOGICAL SPACE OF KOMSOMOLSK-ON-AMUR AMONG YOUNG PEOPLE WITH DIFFERENT MIGRATION INTENTIONS

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2018
The article presents a research of the structure of the socio-psychological space of Komsomolsk-on-Amur among young people with different migration intentions. 130 16–25 year-old residents from Komsomolsk-on-Amur took part in this research.
Anna Vladimirovna Bakina   +2 more
doaj   +1 more source

On Stable Vector Bundles Over Real Projective Spaces [PDF]

open access: yesProceedings of the American Mathematical Society, 1966
If X is a connected, finite CW-complex, we can define (KO)~(X) to be [X, BO] (base-point preserving homotopy classes of maps). Recall [2] that if x E (KO)-(X), the geometrical dimension of x (abbreviated g.dim x) can be defined to be the smallest nonnegative integer k such that a representative of x factors through BO(k). If t is a vector bundle over X,
openaire   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A Generalized Palais-Smale Condition in the Fr\'{e}chet space setting

open access: yesPracì Mìžnarodnogo Geometričnogo Centru, 2018
The Palais-Smale condition was introduced by Palais and Smale in the mid-sixties and applied to an extension of Morse theory to infinite dimensional Hilbert spaces.
Kaveh Eftekharinasab
doaj   +1 more source

Real hypersurfaces of a complex projective space

open access: yesTsukuba Journal of Mathematics, 1999
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

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