Results 121 to 130 of about 16,169,591 (317)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Empty spaces: are Texas office markets on the road to recovery? [PDF]
Real property ; Office ...
D'Ann Petersen
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
CONSIDERATIONS FOR REAL ESTATE PROPERTY VALUATION [PDF]
Risk in Contemporary Economy, 2015 Real estate properties are the most important elements of an economic activity that contributes to the creation of the value once they are included in the economic cycle.The adequate estimate of the value of real estate properties and competent ...
Cristina Mihaela Onica +2 more
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
A comparative analysis on housing policies in Turkey and Lithuania
International Journal of Strategic Property Management, 2007 The housing sector is a very important sector in the national economy worldwide. The greater importance of the housing sector is broadly defined, to include financing, upgrading, repairs, management, valuation, taxation and population.
Feuzullah Yetgin, Natalija Lepkova
doaj
The Howe-Moore property for real and p-adic groups
, 2010 We consider in this paper a relative version of the Howe-Moore Property, about vanishing at infinity of coefficients of unitary representations. We characterize this property in terms of ergodic measure-preserving actions.
Cluckers, Raf +4 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source