Results 111 to 120 of about 3,678,730 (284)

Body representation in old age: the real body versus the social body

open access: yesKairós Gerontologia, 2014
This research is based on the Theory of Social Representations. Due to the cult of the perfect body, handsome young that society has shown, we sought to examine how this cult of the body affects the lives of the elderly. Thus were made interviews with 21
Renato Xavier Coutinho   +2 more
doaj  

Proposing a Data Model for the Representation of Real Time Road Traffic Flow [PDF]

open access: yesDatabase Systems Journal, 2011
Given recent developments in the fields of GIS data modelling, spatial data representation and storage in spatial databases, together with wireless Internet communications, it is becoming more obvious that the requirements for developing a real time road
Alex Alexandru SIROMASCENKO
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Real-Time UAV Tracking Through Disentangled Representation With Mutual Information Maximization

open access: yesIEEE Access
Efficient UAV tracking faces challenges due to limited onboard resources, short battery life, and payload constraints. Discriminative correlation filters (DCF)-based trackers have traditionally been preferred for their efficiency.
Hengzhou Ye   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Faithful real representations of cyclically pinched one-relator groups [PDF]

open access: yesInternational Journal of Group Theory, 2014
In [FR 1,2] using faithful complex representations of cyclically pinched andconjugacy pinched one-relator groups we proved that any limit group has afaithful representation in PSL(2;C). Further this representation can be e ec-tively constructed using the
Benjamin Fine   +2 more
doaj  

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