Results 91 to 100 of about 1,241,819 (264)
Totally real submanifolds in a complex projective space
International Journal of Mathematics and Mathematical Sciences, 1999 In this paper, we establish the following result: Let M be an n-dimensional complete totally real minimal submanifold immersed in CPn with Ricci curvature bounded from below.
Liu Ximin
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Artificial Flooding Leads to Thicker and Brighter Arctic Sea Ice
Earth's FutureWe describe and present results from a 2024/2025 field campaign that is the first to test and observe the impact of flooding and meltwater draining on Arctic sea ice over the winter growth and spring melt seasons.
Edward Blanchard‐Wrigglesworth +26 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
On certain real hypersurfaces of quaternionic projective space
International Journal of Mathematics and Mathematical Sciences, 1991 We classify certain real hypersurfaces ot a quaternionic projective space satisfying the condition σ(R(X,Y)SZ)=0.
Juan De Dios Perez, Florentino G. Santos
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
On nonimmersion of real projective spaces
Topology and its Applications, 2004 The author proves that if \(n=2^r+2^s\;(s\geq 0)\), then the real projective \((16n+11)\)-space \(P^{16n+11}\) cannot be immersed in euclidean \((32n+12)\)-space \(\mathbb{R}^{32n+12}\). This result is the best possible, because Theorem 5 for \(t=1\) of \textit{J. Adem}, \textit{S. Gitler}, and \textit{M. Mahowald} [Bol. Soc. Mat.
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source