Results 131 to 140 of about 6,185,437 (319)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
WCET-aware prefetching of unlocked instruction caches: a technique for reconciling real-time guarantees and energy efficiency [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2015.A computação embarcada requer crescente vazão sob baixa potência. Ela requer um aumento de
Wuerges, Emílio
core
IEEE AccessHybrid electric vehicle power systems (VPSs) comprise of limited energy resources and variable load requirements. The functional status of components and subsystems that make up the VPS is critical to the overall system operation.
Chirath Pathiravasam +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Issues in Active Real-Time Databases
, 1996 Active databases and real-time databases have gained increased interest in recent. Both active and real-time databases are considered as important technologies for supporting non-traditional applications such as computer integrated manufacturing (CIM ...
Mikael Berndtsson +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fundamentals of implementing real-time control applications in distributed computer systems
, 1998 Automatic control applications are real-time systems which pose stringent requirements on precisely time-triggered synchronized actions and constant end-to-end delays in feedback loops which often constitute multi-rate systems.
Törngren, Martin,
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
AORTA: Advanced Offloading for Real-time Applications [Elektronisk resurs]
, 2023 We are currently witnessing the second wave of cloud services that go beyond web storefronts and IT systems, aiming for digitalization of industrial systems. Automation and time-sensitive systems are now taking their first steps toward the cloud.
Mini, Raquel, +9 more
core