Results 41 to 50 of about 568,913 (306)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Philosophy of Chemistry against Standard Scientific Realism and Anti-Realism

open access: yesPhilosophia Scientiæ, 2015
In this paper, it is suggested that philosophy of chemistry can be seen as having quite a central role in the post-Kuhnian philosophy of science in general, and in analysing the scientificc realism vs anti-realism debate in standard philosophy of science,
Rein Vihalemm
doaj   +1 more source

Grounds and Structural Realism: A Possible Metaphysical Framework [PDF]

open access: yes, 2017
This article discusses the proposal of accommodating grounding theories and structural realism, with the aim to provide a metaphysical framework for structural realism.
Savu, Bianca-Alexandra
core  

Surrealism Is Not an Alternative to Scientific Realism [PDF]

open access: yes, 2019
Surrealism holds that observables behave as if T were true, whereas scientific realism holds that T is true. Surrealism and scientific realism give different explanations of why T is empirically adequate.
Park, Seungbae
core   +4 more sources

Cosmological realism [PDF]

open access: yesStudies in History and Philosophy of Science, 2021
I discuss the relevance of the current predicament in cosmology to the debate over scientific realism. I argue that the existence of two, empirically successful but ontologically inconsistent cosmological theories presents difficulties for the realist position.
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Two-setting Bell Inequalities for Graph States [PDF]

open access: yes, 2005
We present Bell inequalities for graph states with high violation of local realism. In particular, we show that there is a two-setting Bell inequality for every nontrivial graph state which is violated by the state at least by a factor of two.
A. Acín   +9 more
core   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Practical Realism: Against Standard Scientific Realism and Anti-Realism

open access: yesStudia Philosophica Estonica, 2012
In this paper, the elaboration of the concept of practical realist philosophy of science which began in the author's previous papers is continued.
Rein Vihalemm
doaj  

Repositioning Realism

open access: yesPhilosophia Scientiæ, 2015
“Naturalised realism” is presented as a version of realism which is more compatible with the history of science than convergent or explanationist forms of realism.
Emma Ruttkamp-Bloem
doaj   +1 more source

Home - About - Disclaimer - Privacy