Results 131 to 140 of about 2,171,590 (329)
Datum: 21.- 23. April 2010 Ort: Fakultät für Angewandte Sozialwissenschaften der Fachhochschule Köln (Mainzer Straße 5, 50678 Köln)
Jennifer Berger
doaj
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Дискурс как контекст функционирования реалий в русском языке
This article is devoted to the study of the problem of the functioning of realities in Russian discourse. This question refers to the functions of realities representing words or expressions unique to a particular language and culture in the context of ...
Hala Jabor, Hisham Hussein
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Augmented Reality, Diminished Reality and Reduced Reality
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Myths and Realities of American Political Geography [PDF]
The division of America into red states and blue states misleadingly suggests that states are split into two camps, but along most dimensions, like political orientation, states are on a continuum.
Bryce A. Ward, Edward L. Glaeser
core
The Tyranny of Numbers: Confronting the Statistical Realities of the East Asian Growth Experience
Alwyn Young
semanticscholar +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source

