Results 31 to 40 of about 3,092 (216)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Educational Academic ResearchCareer, which refers to the sum of an individual's experiences, particularly in the process of acquiring a profession, is not limited to the choice of a particular occupation, but is shaped by the skills and achievements acquired by an individual ...
Saliha Pütüm, Oğuzhan Çelik
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The effect of reality therapy group counseling on pregnant women’s sexual function: An interventional study [PDF]
حیاتBackground & Aim: Pregnant women experience physiological changes and may fear harming themselves or their fetus, leading some to avoid sexual intercourse during pregnancy. This avoidance can lead to sexual health issues.
Fatemeh Bahadori +2 more
doaj
Salāmat-i ijtimā̒ī, 2020 Background and Objective: The growth of divorce in recent years has increased the number of children of divorce and the problems and issues arising from divorce in this sensitive period of development can be strongly influenced by psychological and ...
Abbas Sadeghian +2 more
doaj
A comparative analysis of the effectiveness of reality therapy and cognitive behavioral therapy training on the development of preventive and interventive self-control in incompatible couples [PDF]
Journal of Research in PsychopathologyThe purpose of this study is to provide a comparative analysis of teaching reality therapy and cognitive behavioral therapy on the development of preventive and interventive self-control in incompatible couples.
Leila Mahmoudian +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source