Results 161 to 170 of about 51,523 (265)

How Reusable Are Public Proteomics Datasets in Practice?

PROTEOMICS, EarlyView.
ABSTRACT Public proteomics repositories have expanded rapidly, but large‐scale reuse still depends on whether deposited studies are computationally reusable. We provide an evidence‐based snapshot of this gap by evaluating 500 non‐redundant human ProteomeXchange datasets released in 2025.
Giuseppe G. F. Leite, Victor Corasolla Carregari, Alexandre Keiji Tashima, Reinaldo Salomão   +3 more
wiley   +1 more source

Modeled Subsidence of Permafrost Terrain 2025–2050: North‐Central Alaska

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT A large fraction of the Alaska terrain is underlain by regolith that contains excess ice (ice that in volume exceeds the natural pore space). Possible loss of excess ice would lead to ground subsidence, which in turn would disturb and destabilize the ground surface.
Jaakko Putkonen, Hayden Patterson, Robert Chance, Mary Soaper, Anai Caparó Bellido, Aymane Ahajjam, Andrew Wilcox, Sheridan Parker, Timothy Pasch   +8 more
wiley   +1 more source

LLM-Assisted Reanalysis of Unsolved Rare Disease Genomes Increases Diagnostic Yield. [PDF]

NEJM AI
Jaech A, Cheatham M, Shringarpure SS, Genetti CA, Pradhan P, Bagul A, Panch T, Rader B, Sewalk K, Distler R, Anderson KN, Stewart M, Lejfer S, Glahn DC, Goldstein RD, Wojcik M, Beggs AH, Brownstein JS, Brownstein CA.   +18 more
europepmc   +1 more source

Distinct Conformational Switches Control WPD‐Loop Dynamics Across Protein Tyrosine Phosphatase Subfamilies

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein Tyrosine Phosphatases (PTPs) regulate cellular signaling by balancing phosphotyrosine levels through a conserved WPD‐loop that switches between open (inactive) and closed (active) conformations. While this conformational change is crucial for catalysis, the structural factors governing this motion remain poorly understood.
Colin L. Welsh, Lalima K. Madan
wiley   +1 more source

Intercomparison case study of data-driven reconstructions of a cloud-obscured Saharan dust plume in Europe. [PDF]

Sci Rep
Kanngießer F, Fiedler S.
europepmc   +1 more source

The role of the synoptic‐scale conditions in driving fog and mist during the FATIMA July 2022 Sable Island Field program

Quarterly Journal of the Royal Meteorological Society, EarlyView.
ERA5 hourly 325‐m and 1512‐m (a) convergence and (b) vertical motion (actually pressure change with sign reversed to compare with convergence) over Sable Island around the time of an event. The mist (green) and fog (red) occurrences at the surface station are shown at the bottom of the figures. A 325‐m fitted line convergence was positive for the first
Clive E. Dorman, Darko Koračin, Reneta Dimitrova, Ismail Gultepe, Sebastian W. Hoch, Jesus Ruiz‐Plancarte, Qing Wang, Alexei Perelet, H. J. S. Fernando   +8 more
wiley   +1 more source

Oral metal immunotoxicity in rodents: a recoverability-aware systematic review and within-study quantitative reanalysis of splenic SRBC-TDAR. [PDF]

Front Toxicol
Martínez-Ortiz IC, Garcia-Atutxa I, Machain-Williams C, Reyes-López MÁ, Villanueva-Flores F.   +4 more
europepmc   +1 more source

Acute Post‐Partum Psychosis and Dystonia Reveals Late‐Onset MPAN

Movement Disorders Clinical Practice, EarlyView.
Mathilde Lachaume, Audrey Schalk, Nadège Calmels, Christine Tranchant, Ozanne de Andrade, Fabrice Berna, Mathieu Anheim, Thomas Wirth   +7 more
wiley   +1 more source

Scaling turbulence drives the general circulation

Quarterly Journal of the Royal Meteorological Society, EarlyView.
The NOAA Gulfstream SP4, which deployed the GPS dropsondes over the NE Pacific Ocean as part of the Winter Storms Project during the January–March periods of 2004, 2005 and 2006. Abstract Statistical multifractal analysis of airborne and dropsonde observations is used to show that persistence of velocity after molecular collisions breaks the continuous
Adrian F. Tuck
wiley   +1 more source

From stasis to systematics: deciphering the pathophysiology of secondary lymphedema through omics. [PDF]

Front Immunol
Stull-Lane AR, Chen X, Book AJ, Kratchmarov R, Pal S, Shin J, Ashokan G, Hespe GE, Mehrara BJ, Kataru RP.   +9 more
europepmc   +1 more source