Results 151 to 160 of about 227,373 (338)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Reappraisal of the Role of Alkaline Phosphatase in Hepatocellular Carcinoma [PDF]

, 2022
Chun-Wei Huang, Tsung‐Han Wu, Heng-Yuan Hsu, Kuang‐Tse Pan, Chao‐Wei Lee, Sio-Wai Chong, Song-Fong Huang, Sey‐En Lin, Ming‐Chin Yu, Shen‐Ming Chen   +9 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Positive reappraisal and catastrophizing mediate the relationship between mindfulness and job burnout

Discover Psychology
Mindfulness is well-established as a viable treatment for job burnout. However, the mechanisms underlying mindfulness’s burnout-reducing effect remain unclear.
Fitsum A. Ayele, Kimberly A. Barchard
doaj   +1 more source

Clinical reappraisal of the Composite International Diagnostic Interview Screening Scales (CIDI‐SC) in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)

, 2013
Ronald C. Kessler, Patcho N. Santiago, Lisa J. Colpe, Catherine L. Dempsey, Michael B. First, Steven G. Heeringa, Murray B. Stein, Carol S. Fullerton, Michael J. Gruber, James A. Naifeh, Matthew K. Nock, Nancy A. Sampson, Michael Schoenbaum, Alan M. Zaslavsky, Robert J. Ursano   +14 more
openalex   +2 more sources

The Diffusion of Innovations: A Methodological Reappraisal [PDF]

Studies of diffusion have traditionally relied on specific distributions-primarily the logistic- to characterize and estimate those processes.We argue here that such approach gives rise to serious problems of comparability and interpretation, and may ...
Manuel Trajtenberg, Shlomo Yitzhaki
core  

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Genetic Polymorphism of Sparteine/Debrisoquine Oxidation: A Reappraisal [PDF]

, 1990
M. S. Lennard
openalex   +1 more source

Mapping the interplay among cognitive biases, emotion regulation, and depressive symptoms. [PDF]

, 2017
Buelens, Jana, Duyck, Wouter, Everaert, Jonas, Grahek, Ivan, Koster, Ernst, Van den Bergh, Nathan   +5 more
core   +1 more source