A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Emotional regulation and mental health profiles among Chinese junior middle school students: evidence for the dual-factor model. [PDF]
Guo J, Pan Y, Zhao Y, Liu J, Ye Y.
europepmc +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Emotion regulation as a mediator between stress and burnout in dental postgraduate students: a South China cross-sectional study. [PDF]
Gao X +10 more
europepmc +1 more source
From political to social generations: A critical reappraisal of Mannheim’s classical approach
Sofia Aboim
openalex +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The association of mindfulness with stress self-management among university teachers: the mediating roles of resilience and cognitive reappraisal. [PDF]
Liao S, Hu A.
europepmc +1 more source
Pulmonary Rehabilitation in COPD: A Reappraisal (2008–2012) [PDF]
Pierachille Santus +7 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Laughter regulation in solitary and social contexts varies across emotion regulation strategies. [PDF]
Mitschke V +3 more
europepmc +1 more source

