Results 191 to 200 of about 3,703,656 (252)

Corrugator activity reflects integrated simulation and multifaceted evaluation when processing affective language: Frowning responses to reading about emotions of morally good and bad characters. [PDF]

Cogn Affect Behav Neurosci
Kloostra L, Beulen M, van Berkum JJA, Struiksma ME.   +3 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Delisting From the Kidney Transplant Waiting List: Impact on Patient Survival. [PDF]

Clin Transplant
Schimmers P, Cooper E, Glime W, Asassfeh A, Arpali E, Dunn T, Cooper M, Rawashdeh B.   +7 more
europepmc   +1 more source

Reason, Peter

, 2016
Reason, Peter
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Clinical decision support tool evaluation: Correction of direct oral anticoagulant dosing errors by clinical pharmacists and physicians. [PDF]

Res Pract Thromb Haemost
Saraswat A, Smith SN, Dorsch MP, Fabbri M, Seagull J, Choi SY, Lanham M, Barnes GD.   +7 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Correction to "Balanced Parenting: Proposing a Differentiation-Based Parenting Approach Informed by Bowen Family Systems Theory". [PDF]

Fam Process
europepmc   +1 more source

Acceptability of a Korean Medicine-Based Obesity Program Among Patients Achieving Predefined Weight-Loss Targets: A Retrospective Mixed-Methods Study. [PDF]

Nutrients
Pandey A, Park D, Shin S, Kim J, Kang M, Lee D, Kim J, Kim C, Son J, Jeon S, Bang M, Kang B, Leem J.   +12 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source