Results 101 to 110 of about 4,273,327 (299)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Waterproof pillar size design in steep coal seam

open access: yes矿业科学学报, 2017
According to different combinations of mining methods and water body positions in deep coal seam, three basic structural patterns were created and main basis of setting up reasonable waterproof coal pillar size for each pattern were proposed.
Xu Bin, Dong Shuning, Xu Yanling
doaj  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Sustainability of energy management of transport sector in Hungary [PDF]

open access: yes, 2007
The high ratio of road transportation in CO2 emission caused by humanity made the research of relation between the road transportation and climate change reasonable.
Kosztyó, Ágnes   +2 more
core  

A nonperturbative model for the strong running coupling within potential approach

open access: yes, 2010
A nonperturbative model for the QCD invariant charge, which contains no low-energy unphysical singularities and possesses an elevated higher loop corrections stability, is developed in the framework of potential approach.
A. V. NESTERENKO   +10 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Reconceptualising the third sector: toward a heterodox perspective [PDF]

open access: yes
The paper explores the way the work of classic institutionalist authors can inform modern nonprofit economics. From the perspective of Thorstein Veblen, nonprofit organisation is explained as an institutional consequence of the pecuniary-industrial ...
Vladislav Valentinov
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

New methods for deprecating artificial intelligence systems will preserve history and facilitate research

open access: yesNature Communications
AI developers and policy makers need to devise methods of commercial model deprecation that balance developers’ reasonable interest in restricting access to outdated models with the value of preserving technological developments and enabling ongoing ...
Tim Johnson, Nick Obradovich
doaj   +1 more source

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