Results 141 to 150 of about 9,024,391 (348)

Voluntary abortion in Iran: a qualitative study

Payesh, 2007
Objective(s): Voluntary abortion is one of the main causes of maternal mortality and morbidity worldwide. Despite the legal ban and the existing socio-cultural obstacles, women still are contemplating abortion in Iran.
Chinichian M, Holakoic Nainie K, Rafaie Shirpak Kh   +2 more
doaj  

Alasan Gugat Cerai Pada Perkawinan Di Bawah Umur Di Kabupaten Sleman

Asas wa Tandhim
Based on case data received at the Sleman Regency Religious Court in 2021–2022, there has been an increase in the number of divorce cases, with 76% of the total cases being divorce lawsuits filed by wives, while 24% were divorce lawsuits filed by ...
Tri Ratna Herawati, Muthmainnah Muthmainnah, Cipto Sembodo, Ika Kartika Sari, Sahril Fadli   +4 more
doaj   +1 more source

Notwithstanding Bohr, the Reasons for QBism [PDF]

, 2017
Christopher A. Fuchs
openalex   +1 more source

Reasons, rationality, reasoning: how much pulling-apart? [PDF]

, 2018
At the heart of John Broome’s research program in the philosophy of normativity is a distinction between reasons, on one hand, and requirements of rationality, on the other.
Worsnip, Alex
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Reasons and impacts of alcohol use disorder among ethnic minority young adults: a descriptive phenomenological study

Frontiers in Public Health
IntroductionAlcohol use disorder (AUD) is prevalent among ethnic minority young adults. However, there is limited evidence exploring its health impact and contributing factors in ethnically marginalized young adults.
Getaneh Mulualem Belay, Mak Yim Wah, Katherine Ka Wai Lam, Qi Liu, Mao Ting, Chen Xi, Funa Yang, Cynthia Sau Ting Wu, Ka Yan Ho   +8 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source