Results 111 to 120 of about 605,528 (306)
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Religious Disagreement in Analytic Theology
Religious disagreement means holding incompatible views of the truth or of the plausibility of some position that is religiously relevant. It is well known that many religious and non-religious worldviews make apparently incompatible claims about ...
Olli-Pekka Vainio
doaj
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Recognising Agreement and Disagreement between Stances with Reason Comparing Networks [PDF]
Chang Xu +3 more
openalex +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Waarom verskil ons so oor wat die wil van God is? Opmerkings oor Christelike morele oordeelsvorming
Why do we differ so much about the will of God? Comments on the formation of Christian moral judgements A better understanding of the way in which moral judgements are made and moral decisions are taken may help to understand why Christians differ so ...
D. E. de Villiers, D. J. Smit
doaj +1 more source
The Attempt to Improve Criminal Defense Representation [PDF]
Improvement of criminal defense representation is one of the most critical problems that faces the criminal justice system. The problem is extensive; some attorneys are frequently ineffective and probably all attorneys are occasionally inadequate because
Tague, Peter W.
core +1 more source
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Reconciling Enkrasia and Higher-Order Defeat [PDF]
Titelbaum Oxford studies in epistemology, 2015) has recently argued that the Enkratic Principle is incompatible with the view that rational belief is sensitive to higher-order defeat.
Skipper, Mattias
core

