Results 51 to 60 of about 607,703 (364)

Talking about Taste: Disagreement, Implicit Arguments and Relative Truth [PDF]

open access: yes, 2007
In this paper, I take issue with an idea that has emerged from recent relativist proposals, and, in particular, from Lasersohn (2005), according to which the correct semantics for taste predicates must use contents that are functions of a judge parameter
Stojanovic, Isidora
core   +3 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

First Person and Third Person Reasons and Religious Epistemology [PDF]

open access: yes, 2011
In this paper I argue that there are two kinds of epistemic reasons. One kind is irreducibly first personal -- what I call deliberative reasons. The other kind is third personal -- what I call theoretical reasons.
Zagzebski, Linda
core  

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

On the sodium overabundance of giants in open clusters: The case of the Hyades

open access: yes, 2012
Sodium abundances have been determined in a large number of giants of open clusters but conflicting results, ranging from solar values to overabundances of up to five orders of magnitude, have been found.
Allende Prieto   +93 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Micromagnetic simulations of the magnetization precession induced by a spin polarized current in a point contact geometry

open access: yes, 2006
This paper is devoted to numerical simulations of the magnetization dynamics driven by a spin-polarized current in extended ferromagnetic multilayers when a point-contact setup is used.
D. V. Berkov, Doering W., N. L. Gorn
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A Critical Review of Arguments of Mulla Rajab Ali Tabrizi on Homonymy of Existence [PDF]

open access: yesحکمت صدرایی, 2020
Mulla Rajabali Tabrizi, one of the philosophers of the Safavid Era in Isfahan, is among the philosophers who have criticized Sadra regarding the principles of transcendent wisdom. One of these principles is the Homonymy or Polysemy of existence.
Jabbar Amini   +2 more
doaj  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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