Results 121 to 130 of about 304,891 (277)

“…The Old Crimean Khan Went to the Mountain Circassians”: The Residence of Dethroned Khan Devlet Giray II in the Northern Caucasus (1703)

open access: yesЗолотоордынское обозрение
Research objectives: The aim of this article is to establish new historical details related to Devlet Giray II’s escape to the North Caucasus in the spring of 1703 after his impeachment and the crushing of his rebellion.
Sen’ D.V.
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

The Moral Economy of the Penal Crowd: The Microhistory of a Pre-War Prison Strike

open access: yesHistories
Historical discussions regarding labour organizing within American prisons tend to focus on the period stretching from the late 1950s to the early 1970s, framing those years as both the origin and apex of nationalized and organized inmate-led strikes ...
Alex Tepperman
doaj   +1 more source

Inclusive Institutions and the Onset of Internal Conflict in Resource-rich Countries [PDF]

open access: yes
The literature on institutional determinants of intra-state violence commonly asserts that the presence of multiple political parties reduces the conflict potential within countries; by co-opting oppositional groups into an institutionalized political ...
Tim Wegenast
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Interview with Marcus Rediker

open access: yesDiacronie. Studi di Storia Contemporanea, 2013
The following is an expanded version of an interview with Marcus Rediker, a shortened version of which was first published in Pittsburgh City Paper. This new version also includes additional material supplied by Marcus Rediker.
Bill O’Driscoll is Arts & Entertainment Editor of Pittsburgh City Paper, a weekly newspaper for which he writes about books, theater, film and visual art, as well as about environmental issues.
doaj  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy