Results 151 to 160 of about 304,891 (277)

Youth Appeal in Tobacco Advertising: Evolving Tactics Targeting Those Under the Legal Age of Sale. [PDF]

Subst Use Misuse
Frisbee S, Czaplicki L, Ibrahim M, Kennedy RD, Moran MB.   +4 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

The role of control in precipitating and motivating self-harm in young people: A systematic review and meta-synthesis of qualitative data. [PDF]

PLoS One
Rheinberger D, Slade A, Tang B, Hoye A, Fujimoto H, Zheng WY, Holmes G, Boydell K, Calear AL, Christensen H, Tang S.   +10 more
europepmc   +1 more source

Democracy and Nobility

, 2015
Americans love revolutions. Our national identity began with a revolution, and a revolutionary war that lasted for eight years; and we cheer on other people’s revolutions, as though we find satisfaction in multiplying our own.
Guelzo, Allen C.
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Promoting adolescents' pro-environmental behavior: A motive-alignment approach. [PDF]

J Res Adolesc
van de Wetering J, Grapsas S, Poorthuis A, Thomaes S.   +3 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

How scientists can contribute to the social movements essential to protecting climate and nature. [PDF]

NPJ Clim Action
Perrin AJ, Capstick S, Elliott T, Knapp P, Thierry A, Wyatt TD, Gardner CJ.   +6 more
europepmc   +1 more source

The Memory of Battle Surrounds You Once Again: Iowa Grand Army of the Republic Reunions and the Formation of a Pro-Union Nationalism, 1886-1949

, 2015
Following the bloody years of the Civil War, veteran organizations became a breeding ground for nationalism making and memory shaping. Historians, like Caroline Janney and David Blight, have debated what these memories meant for northern veterans.
Bautz, Peter
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source