Results 111 to 120 of about 8,181,745 (306)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

IMPROVEMENT OF COMPRESSIBLITY CHARCTERISTICSOF NATURAL ORGANIC SOILS

Journal of Engineering and Sustainable Development, 2018
The aim of this paper is to investigate the possible improvement of the compressibility characteristics (compression index, rebound index, i.e.,)of natural organic soil by using cement dust and fly ash. Natural organic soil with different percentages of
Adel Hamed Majeed, Abbas Adday Al Zayadi, Jasim Mohammed Abdul Abbas   +2 more
doaj  

GEL-LightGBM: A Gated Empirical-Law Framework for Interpretable Prediction of Rock Uniaxial Compressive Strength

Applied Sciences
Uniaxial compressive strength (UCS) is a fundamental parameter for rock engineering design and stability assessment, but direct laboratory testing is costly, time-consuming, and often difficult for weak or fractured rocks.
Jie Peng, Hengyu Liu, Yun Lin, Yanyan He
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Experimental study on comparison of consolidation creep characteristics between silty sand and silty soil

Yantu gongcheng xuebao
n order to explain the lagging settlement in the surrounding ground induced by pre-dewatering of excavations, one-dimensional consolidation creep tests are conducted on typical silty sand and silty soil at a metro station site of Jiangsu Province.
ZHU Jun 1, CHEN Shaobo 2, YING Xu 2, ZHOU You 2, ZHANG Siyu 3
doaj   +1 more source

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Application of lichenometry and residual strength test for age estimation of Holocene moraines in the Suntar-Khayata Mountains

Лëд и снег, 2015
Residual strength and diameters of lichen Rhizocarpon sp. were measured on different elements of the Late Holocene glacial-cryogenic morphosculpture of frontal parts of glaciers № 29 and 31 in the Suntar-Khayat Range. All in all, 180 lichenometric sites (
A. A. Galanin, V. M. Lytkin, B. A. Shishkov   +2 more
doaj   +1 more source

The added value from a general equilibrium analysis of increased efficiency in household energy use [PDF]

, 2013
This paper investigates the economic impact of a 5% improvement in the UK household energy efficiency, focussing specifically on total energy rebound effects.
Turner, Karen, McGregor, Peter, Swales, J. Kim, McGregor, Peter G., Lecca, Patrizio   +4 more
core   +1 more source