Results 81 to 90 of about 32,451 (248)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Inter-day reliability and usefulness of reactive strength index derived from two maximal rebound jump tests

open access: yes, 2019
Purpose: This investigation examined the inter-day reliability and usefulness of reactive strength index (RSI) derived from a maximal 5 rebound jump test (5max RJT) and a maximal 10 rebound jump test (10/5 RJT). Methods: Twenty male field sport athletes (24.5±3.0 y; 1.78±0.1 m; 84.9±5.2 kg) performed 2 maximal repetitions of the 5max RJT and the 10/5 ...
Comyns, Thomas M.   +4 more
openaire   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

IMPROVEMENT OF COMPRESSIBLITY CHARCTERISTICSOF NATURAL ORGANIC SOILS

open access: yesJournal of Engineering and Sustainable Development, 2018
The aim of this paper is to investigate the possible improvement of the compressibility characteristics (compression index, rebound index, i.e.,)of natural organic soil by using cement dust and fly ash. Natural organic soil with different percentages of
Adel Hamed Majeed   +2 more
doaj  

GEL-LightGBM: A Gated Empirical-Law Framework for Interpretable Prediction of Rock Uniaxial Compressive Strength

open access: yesApplied Sciences
Uniaxial compressive strength (UCS) is a fundamental parameter for rock engineering design and stability assessment, but direct laboratory testing is costly, time-consuming, and often difficult for weak or fractured rocks.
Jie Peng, Hengyu Liu, Yun Lin, Yanyan He
doaj   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Experimental study on comparison of consolidation creep characteristics between silty sand and silty soil

open access: yesYantu gongcheng xuebao
n order to explain the lagging settlement in the surrounding ground induced by pre-dewatering of excavations, one-dimensional consolidation creep tests are conducted on typical silty sand and silty soil at a metro station site of Jiangsu Province.
ZHU Jun 1, CHEN Shaobo 2, YING Xu 2, ZHOU You 2, ZHANG Siyu 3
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

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