A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
Cognitive Reserve and Its Relationship With Memory Changes: An Analysis of the Survey of Health, Aging, and Retirement in Europe (SHARE). [PDF]
Melendez JC +2 more
europepmc +1 more source
The Effect of Suvorexant on Fear Extinction Recall: A Double‐Blind Randomised Controlled Pilot Trial in Healthy Individuals [PDF]
Maya T. Schenker +10 more
openalex +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Barcode activity in a recurrent network model of the hippocampus enables efficient memory binding. [PDF]
Fang C +4 more
europepmc +1 more source
Visual attention and recall of spatial locations of briefly presented words
Ling-Po Shiu
openalex +1 more source
Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao +15 more
wiley +1 more source
Protein synthesis blockade prevents fear memory reactivation via inhibition of engram synapse strengthening. [PDF]
Hong I +5 more
europepmc +1 more source

